Interactive RadioEpidemiological Program


For Estimating Probability of Cancer Causation for Exposures to Radiation

To begin by manually entering required inputs
To begin by using a NIOSH-provided input file
To calculate PC from multiple primary cancers

NIOSH-IREP was created for use by the Department of Labor for adjudication of claims in accordance with the Energy Employees' Occupational Illness Compensation Program Act of 2000 (EEOICPA). NIOSH-IREP was adapted from the National Institutes of Health's (NIH) Interactive RadioEpidemiological Program (IREP) developed by the National Cancer Institute (NCI) to update the NIH Radioepidemiological Tables of 1985. (The version of IREP developed by NCI is known as NIH-IREP.)

Click here for details about the modifications made to the current version of NIOSH-IREP and to other recent versions. Comments and suggestions should be communicated directly to

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With modeling support from: